Cognitive Decline

Effects of novel Cognitive Stimulating Activities (CSAs) on cognition and depression: A 5-year pragmatic and naturalistic study

This five-year follow-up study looked at whether older Singaporeans who had earlier taken part in activities like mindfulness, gardening, art, or choir singing had better thinking skills and fewer depressive symptoms later on, compared with those who hadn’t.

Effects of novel Cognitive Stimulating Activities (CSAs) on cognition and depression: A 5-year pragmatic and naturalistic study Read More »

Prevalence, risk and protective factors for mild cognitive impairment in a population-based study of Singaporean elderly

In a large Singapore survey, about 1 in 8 elderly people had mild memory problems. Men were more likely to have the type mainly affecting memory, while women were more likely to have the type affecting other thinking skills, like planning or attention.

Prevalence, risk and protective factors for mild cognitive impairment in a population-based study of Singaporean elderly Read More »

Increased plasma brain-derived neurotrophic factor (BDNF) as a potential biomarker for and compensatory mechanism in Mild cognitive impairment: A case-control study

This study found that a brain-growth protein called BDNF was actually higher, not lower, in the blood of older adults with mild memory problems compared with healthy peers, and could reliably tell the two groups apart. The researchers suggest this rise may be the brain’s way of compensating for early decline.

Increased plasma brain-derived neurotrophic factor (BDNF) as a potential biomarker for and compensatory mechanism in Mild cognitive impairment: A case-control study Read More »

Mindfulness Awareness Practice (MAP) to Prevent Dementia in Older Adults with Mild Cognitive Impairment: Protocol of a Randomized Controlled Trial and Implementation Outcomes

This study protocol describes a trial testing whether mindfulness training can help prevent dementia in older adults with mild memory problems, tracking effects on thinking skills as well as a range of blood and brain markers linked to ageing.

Mindfulness Awareness Practice (MAP) to Prevent Dementia in Older Adults with Mild Cognitive Impairment: Protocol of a Randomized Controlled Trial and Implementation Outcomes Read More »

Regression-Based Norms and Validation of the Cambridge Neuropsychological Test Automated Battery among Community-Living Older Adults in Singapore

This study created local Singapore benchmarks for a set of computerized memory and thinking tests, using data from 210 older adults, and checked how well these newer tests matched up with traditional pen-and-paper tests.

Regression-Based Norms and Validation of the Cambridge Neuropsychological Test Automated Battery among Community-Living Older Adults in Singapore Read More »

The functional and structural connectomes associated with geriatric depression and anxiety symptoms in mild cognitive impairment: Cross-syndrome overlap and generalization

This brain-scan study looked at how depression and anxiety symptoms relate to brain connectivity patterns in older adults with mild memory problems, finding some overlapping but also some distinct brain networks linked to each type of symptom.

The functional and structural connectomes associated with geriatric depression and anxiety symptoms in mild cognitive impairment: Cross-syndrome overlap and generalization Read More »

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