Cognitive Decline

Mindfulness intervention for mild cognitive impairment led to attention-related improvements and neuroplastic changes: results from a 9-month randomized control trial

This trial found that nine months of mindfulness training improved attention-related thinking skills and was linked to a thickening in a brain region tied to attention, compared with a health education programme, in older adults with mild memory problems.

Mindfulness intervention for mild cognitive impairment led to attention-related improvements and neuroplastic changes: results from a 9-month randomized control trial Read More »

Horticultural Therapy Reduces Biomarkers of Immunosenescence and Inflammaging in Community-Dwelling Older Adults: A Feasibility Pilot Randomized Controlled Trial

This trial found that a gardening programme reduced signs of immune system ageing and chronic low-level inflammation in older Singaporean adults, giving biological evidence that gardening can help counter age-related decline in the immune system.

Horticultural Therapy Reduces Biomarkers of Immunosenescence and Inflammaging in Community-Dwelling Older Adults: A Feasibility Pilot Randomized Controlled Trial Read More »

Commonalities in Biomarkers and Phenotypes between Mild Cognitive Impairment and Cerebral Palsy: A Pilot Exploratory Study

This early exploratory study compared body markers and physical traits between older adults with mild memory problems and younger adults with cerebral palsy, finding some shared features that may point to a common pattern of ‘faster ageing’ in both groups.

Commonalities in Biomarkers and Phenotypes between Mild Cognitive Impairment and Cerebral Palsy: A Pilot Exploratory Study Read More »

Effects of choral singing versus health education on cognitive decline and aging: a randomized controlled trial

In a two-year trial, older Singaporeans at risk of dementia who joined a weekly choir showed a small but real improvement in thinking skills compared with those who received health education instead, though no differences showed up on brain scans or ageing markers.

Effects of choral singing versus health education on cognitive decline and aging: a randomized controlled trial Read More »

The individualized prediction of cognitive test scores in mild cognitive impairment using structural and functional connectivity features

This study used brain scan data and computer models to predict how well older adults with mild memory problems would score on 10 different thinking tests, aiming to reduce the need for long, sometimes unreliable memory testing sessions.

The individualized prediction of cognitive test scores in mild cognitive impairment using structural and functional connectivity features Read More »

The functional and structural connectomes of telomere length and their association with cognition in mild cognitive impairment

Using brain scans of 82 older adults with mild memory problems, this study linked how well-connected the brain is to telomere length (a marker of cellular ageing), and showed this connection could help predict memory and planning test scores.

The functional and structural connectomes of telomere length and their association with cognition in mild cognitive impairment Read More »

Arts-based interventions to improve cognition in older persons with mild cognitive impairment: A systematic review of randomized controlled trials

Reviewing 11 trials, this study found that creative activities — including visual arts, dance, music, and storytelling — generally improved memory and overall thinking skills in older people with mild cognitive decline, though the quality of evidence varied.

Arts-based interventions to improve cognition in older persons with mild cognitive impairment: A systematic review of randomized controlled trials Read More »

Effect of mindfulness intervention versus health education program on salivary Aβ-42 levels in community-dwelling older adults with mild cognitive impairment: A randomized controlled trial

This trial tested whether mindfulness training could lower a saliva marker linked to Alzheimer’s disease in older adults with mild memory problems, compared with a health education programme, extending earlier findings on mindfulness and body markers of brain health.

Effect of mindfulness intervention versus health education program on salivary Aβ-42 levels in community-dwelling older adults with mild cognitive impairment: A randomized controlled trial Read More »

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